Webinar I March 18, 2024
DISCOVER protein-DNA conjugate purification: Effortless conjugate preparation, purification, and analysis with the proFIRE®
This is the second episode of the second season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge drug discovery topics like bispecific antibodies, PROTACs or small molecules targeting RNA. We will show you how to characterize the respective molecular interactions in depth, how to create assays with remarkable biological similarity, low sample consumption, high versatility and exceptional ease-of-use. In this episode we talk about sample preparation, more specifically about the preparation and purification of protein-DNA conjugates. Protein-DNA conjugates are crucial not only for kinetic measurements withswitchSENSE®, but also in many other areas like DNA nanotechnology and protein detection. We introduce the proFIRE® system for intuitive and effortless purification and show example use cases from literature ranging from antigen-conjugated nucleic acids for point-of-care detection to antibodies coupled to ssDNA for the functionalization of complex DNA origami structures. If you are interested in another application, you can find all future episodes of this webinar series here.