Read full Article Publication I April 01, 2021 Macromolecular interactions in vitro, comparing classical and novel approaches Biophysical quantification of protein interactions is central to unveil the molecular mechanisms of cellular processes. Researchers can choose...
Read full Article Publication I March 30, 2021 CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS Through dominant mutations, aminoacyl-tRNA synthetases constitute the largest protein family linked to Charcot-Marie-Tooth disease (CMT). An...
Read full Article Publication I March 27, 2021 Standard operation procedure for switchSENSE DRX systems There is currently a large panel of technologies available to address molecular interactions in vitro. Each technology presents individual advantages and drawbacks,...
watch tutorial Tutorial I January 2021 Multiplex DNA Binder Tutorial In this 20 min tutorial, learn how easy it is to measure kinetics of a DNA-binding protein to 4 targets simultaneously with our new heliX® biosensor. We are analyzing association and dissociation...
Read full Article Publication I December 11, 2020 switchSENSE technology for analysis of DNA polymerase kinetics The switchSENSE technology is a recent approach based on surface sensor chips for the analysis of interactions of macromolecules. The technology relies on...
