Read full Article Publication I June 09, 2020 The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies The cytokine tumor necrosis factor-alpha (TNF-α) readily forms homotrimers at...
Read full Article Publication I August, 2020 DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease Repair of covalent DNA-protein crosslinks (DPCs) by DNA-dependent proteases has emerged as an essential genome maintenance mechanism required...
Read full Article Publication I July 2, 2020 Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens Signaling molecule receptors play a central role in quorum sensing and in the...
Read full Article Publication I May, 2020 A compact nanobody-DNAzyme conjugate enables antigen detection and signal amplification Hemin-utilizing G-quadruplex DNAzymes with peroxidase-like (POX) activity are widely used as signal reporters in biosensing technology....
Read full Article Publication I May 12, 2020 Single-Molecule Sensing of DNA Intercalating Drugs in Water The occurrence of pharmaceutical residues in surface water is raising environmental concern. To accompany the evolution of measures for natural resources...