Read App Note App Note I January 9, 2020 Site-specific covalent conjugation and purification of His-tagged proteins to DNA for switchSENSE® applications In this application note, we introduce a conjugation kit for a straightforward, site-selective and covalent...
Read full Article Publication I September 9, 2019 CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells Aminoacyl-transfer RNA (tRNA) synthetases (aaRSs) are the largest protein...
Read full Article Publication I August 8, 2019 A DNA-based biosensor assay for the kinetic characterization of ion-dependent aptamer folding and protein binding Therapeutic and diagnostic aptamers are nucleic acid oligomers designed to bind tightly and specifically...
Read full Article Publication I May 29, 2019 A Step-by-Step Guide to Study Protein–RNA Interactions Protein–RNA complex formation is at the center of RNA metabolism and leads to the modulation of protein and RNA functions. We propose here a step-by-step guide to...
Read full Article Publication I December 11, 2020 Triazine-Modified 7-Deaza-2′-deoxyadenosines: Better Suited for Bioorthogonal Labeling of DNA by PCR than 2′-Deoxyuridines 6-Ethynyl-1,2,4-triazine is a small bioorthogonally reactive group we applied for fluorescent...
