App Note I May 17, 2017 List of protein hydrodynamic diameters DH ProteinMolecular weightDH measured with switchSENSE® (i)Dh calculated from PDB file (ii)PDB codeStructure anti-human Fab fragment050 kDa06.6 nm07.2 nm3WD5 anti-human IgG150 kDa12.7 nm11.2 nm1IGT...
Read App Note App Note I January 22, 2016 Real-time measurement of nickel ion chelation kinetics Nitrilotriacetic acid (NTA) is a common chelating agent, which forms coordination compounds with metal ions (chelates) such as Ni2+, Cu2+ and Co2+. It is primarily used...
Read App Note App Note I January 17, 2016 Real-time measurements of DNA exonucleases The activities of the 5’→3’ exonucleases T5 exonuclease and Lambda exonuclease could be analyzed using a switchSENSE molecular ruler assay. The assay can be applied for evaluating...
Read App Note App Note I July 13, 2015 Characterization of a high-affinity anti-EPO antibody by switching speed measurements Erythropoietin (EPO) is a glycoprotein that upregulates the production of red blood cells. Recombinantly produced EPO is used as a drug to...
Read App Note App Note I January 25, 2014 Nanolever temperature stabilitystandard DNA nanolever The oligodeoxynucleotides used as standard nanolevers have been selected to maintain their double stranded conformation even at high temperatures and can be used up to 70°C...
