Read full Article Publication I January 18, 2024 DNA origami traps for large viruses Virus-enveloping macromolecular shells or tilings can prevent viruses from entering cells. Here, we describe the design and assembly of a cone-shaped DNA origami higher-order assembly...
Read full Article Publication I December 7, 2023 Kinetic FRET Assay to Measure Binding-Induced Conformational Changes of Nucleic Acids The interaction of small molecules or proteins with RNA or DNA often involves changes in the nucleic acid (NA) folding and structure....
Read full Article Publication I November 27, 2023 Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction The classical Non-Homologous End Joining (c-NHEJ) pathway is the predominant process in mammals...
View Webinar Webinar I November 15, 2023 DISCOVER high throughput kinetic characterization of engineered multivalent peptide based inhibitors. This is the seventh episode of our DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge...
View Webinar Webinar I October 16, 2023 DISCOVER protein conformational changes with electrically actuated DNA origami nanolevers. This is the sixth episode of our DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge drug...