Read full Article Publication I December 1, 2022 Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab The binding properties of bispecific antibodies (bsAb) are crucial for their function, especially when two antigens are targeted...
Read full Article Publication I January 13, 2023 The Impact of Nε-Acryloyllysine Piperazides on the Conformational Dynamics of Transglutaminase 2 In addition to the classic functions of proteins, such as acting as a biocatalyst or binding partner, the conformational...
Read More App Note switchSENSE® Compatibility Sheet The switchSENSE® compatibility provides an overview on different conditions switchSENSE® measurements can be performed in. ...
Download Brochure Brochure I November 1, 2022 Drugging the “undruggables” Overcome the challenge of analyzing small molecules that inhibit or stabilize protein-protein interactions. Create Homo- or Hetero-protein immobilizationon the biosensor...
Read full Article Publication I October 27, 2022 Structural basis for Cas9 off-target activity The target DNA specificity of the CRISPR-associated genome editor nuclease Cas9 is determined by complementarity to a 20-nucleotide segment in its guide RNA. However, Cas9...