In rare cases, it is possible that a leak occurs in the DRX chip holder. This will not cause damage to the DRX sensor system as all ongoing measurements and fluidic steps will automatically be stopped by the switchCONTROL software. In the event of a leak during a...
switchSENSE® chips are generally robust and long-lasting, if handled and stored under recommended conditions. Instructions for chip storage: Store the chip at 4 °C in its original packing, whenever it is not used for experiments. Do not freeze a switchSENSE® chip! To...
switchSENSE® chips are very versatile, typically long-lasting and can be used for a multitude of different experiments, due to the possibility of chip regeneration. During the course of the experiments, the sensor electrodes are subjected to a certain decrease of...
Briefly, the answer is yes. Decrease in the absolute fluorescence intensity is completely normal during switchSENSE® experiments. There are several factors that can affect the fluorescence emission, for instance photobleaching, chemical and thermal stress on the...
Chip regeneration implies that all ligand molecules immobilized on switchSENSE® electrodes in one flow channel and all potentially bound analyte molecules are completely washed off the sensor surfaces by treatment with a regeneration solution. This leaves...